8:00 AM - 8:30 AM

Registration & Coffee

8:30 AM - 10:30 AM

Session I.mRNA metabolism in human cancers: beyond transcription

Session Organizer: Andrei Thomas-Tikhonenko

Internal Speakers

Gideon Dreyfuss
"Telescripting: overarching gene control mechanism and cancer cell phenotype"

Kristen Lynch 
“Alternative splicing and the human immune system”

Andrei Thomas-Tikhonenko
"Aberrant exon usage in the pathogenesis of B-cell acute lymphoblastic leukemia"

Russ Carstens
“Characterization of an alternative splicing program that is essential for epithelial cell function and mammalian development”

Jeremy Wilusz
"Rewiring translation: Identifying conditions when non-AUG start codons are preferred"

External Speakers

Omar Abdel-Wahab (MSKCC) 
"Understanding and Targeting Spliceosomal Gene Mutations in Leukemias."

10:30 AM - 10:45 AM

 Coffee Break

10:45 AM - 12:45 PM

Session II.Beyond messenger RNAs: Non-coding RNAs and their binding partners 

Session Organizer: Lin Zhang

Internal Speakers

Alessandro Gardini
“The Integrator protein complex at the enhancer-promoter crossroads”

Chris Lengner
"Msi RNA Binding Proteins in Intestinal Stem Cells and Cancer"

Qihong Huang
"Lost in Translation: A Long Non-coding RNA Regulates Metastasis at the Translational Step"

Lin Zhang
“Genomic alterations of long non-coding RNA in cancer

 

External Speakers

Myriam Gorospe (NIH)
Noncoding RNPs in Cell Senescence

Eva Hernando-Monge (NYU)
"Role of circular RNA in melanoma progression"

12:45 PM – 1:45 PM

Lunch & Poster Setup

1:45 PM – 3:45 PM

Session III. New approaches to studying RNA: biochemistry meets bioinformatics

Session Organizer: Zissimos Mourelatos

Internal Speakers

Sara Cherry
"Using functional genomics to inform treatments in cancer"

Yoseph Barash
"Scaling RNA-Seq splicing analysis for hundreds and thousands of samples"

 Arjun Raj
“Single cell analysis of resistance to targeted therapy in cancer”

Zissimos Mourelatos
"Hidden lifestyles of messenger RNAs"
 

External Speakers

Karla Neugebauer (Yale)
“Single molecule RNA-seq reveals coupling among RNA processing events”

Isidore Rigoutsos (Jefferson)
“Transcriptomic Heterogeneity of Short Non-coding RNAs in Healthy People and in Patients”



3:45 PM – 4:30 PM

Session IV. Poster Viewing & Refreshments

Session Organizer: Kristen Lynch

4:30 PM – 5:15 PM

Session V. Keynote Address

Adrian Krainer (CSHL)

"Alternative mRNA splicing in cancer"

5:15 PM – 5:30 PM

Poster Awards - sponsored by RNA Society